【報告題目】: Hormonal Control of Shoot Branching

【報 告 人】: Prof. Dr. Ottoline Leyser

英國皇家學會會士

美國科EON4外籍院士

Sainsbury Laboratory

University of Cambridge

Bateman Street

CB2 1LR, UK

【報告時間】: 2013年6月17日（星期一）上午09:30時

【報告地點】: EON体育4平台3-105號會議室

【聯系人】：  張大兵 教授

報告人背景介紹：

Education

BA. Hons. Genetics, Newnham College, Cambridge (1983-1986)

PhD Genetics, Newnham College, Cambridge (1986-1990)

Career

Department of Biology, Indiana University (1990-1993)

Post-doctoral researcher in the laboratory of Prof Mark Estelle

Department of Genetics, University of Cambridge (1993-1994)

Post- doctoral researcher in the laboratory of Dr Ian Furner

Department of Biology, University of York (1994-2010)

Lecturer 1994, Reader 1999, Professor 2002

Sainsbury Laboratory, University of Cambridge (2011-)

Professor of Plant Development and Associate Director

Fellow of Clare College (2012-)

Fellowships

AFRC 2+1 Post-doctoral Research Fellowship (1991-1994)

Jenner Research Fellowship, Newnham College, Cambridge (1993-1994)

BBSRC Research Development Fellowship (2001-2003)

Moore Distinguished Scholarship, California Institute of Technology, USA (2003)

Royal Society Wolfson Research Merit Award (2009-2011)

Awards, Honours and Prizes

KM Stott Research Fellowship Prize, Newnham College, Cambridge (1993)

Society for Experimental Biology President’s Medal (2000)

Royal Society Rosalind Franklin Award (2007)

Elected a Fellow of the Royal Society (2007)

Elected a Member of EMBO (2007)

Appointed Commander of the Order of the British Empire (2009)

University of York Vice-Chancellor’s Teaching Award (2009)

International Plant Growth Substance Association Silver Medal (2010)

Elected Foreign Associate, National Academy of Sciences USA (2012)

Editorial Positions

Current Opinion in Plant Biology, Co-editor in Chief 2009-

Science, Board of Reviewing Editors 2010-

Development, Editor 2011-

Philosophical Transactions of the Royal Society B, Editor 2011-

Proceedings of the National Academy of Science USA 2012-

Selected publications since 2002

1.        Stirnberg P, van de Sande K, Leyser HMO (2002) MAX1 and MAX2 control shoot lateral branching in Arabidopsis. Development 129:1131-1141

2.        Booker JP, Chatfield SP, Leyser O (2003) Auxin acts in xylem-associated or medullary cells to mediate apical dominance. Plant Cell 15:495-507

3.        Sorefan K, Booker J, Haurogné K, Goussot M, Bainbridge K, Foo E, Chatfield S, Ward S, Beveridge C, Rameau C, Leyser O (2003) MAX4 and RMS1 are orthologous dioxygenaselike genes that regulate shoot branching in Arabidopsis and Pea. Genes and Development 17:1469-1474

4.        Knox K, Greirson CS, Leyser O (2003) AXR3 and SHY2 interact to regulate root hair development. Development 130:5769-5777

5.        Booker J, Auldridge M, Wills S, McCarty D, Klee H, Leyser O (2004) MAX3/CCD7 is a carotenoid cleavage dioxygenase required for the synthesis of a novel plant signaling molecule. Current Biology 14:1231-1238

6.        Kepinski S, Leyser O (2004) Auxin-induced SCFTIR1-Aux/IAA interaction involves stable modification of the SCFTIR1 complex. Proceedings of the National Academy of. Science USA 101:12381-12386

7.        Booker J, Sieberer T, Wright W, Williamson L, Willett B, Stirnberg P, Turnbull C, Srinivasan M, Goddard P, Leyser O (2005) MAX1 encodes a cytochrome P450 family member that acts downstream of MAX3/4 to produce a carotenoid-derived branch-inhibiting hormone. Developmental Cell. 8:443-449

8.        Kepinski S, Leyser O (2005) The Arabidopsis F-box protein TIR1 is an auxin receptor. Nature 435:446-451

9.        Bennett T, Sieberer T, Willett B, Booker J, Luschnig C, Leyser O (2006) The Arabidopsis MAX pathway controls shoot branching by regulating auxin transport. Current Biology 16:553-563

10.    Stirnberg P, Furner I, Leyser O (2007) MAX2 participates in an SCF complex which acts locally at the node to suppress shoot branching. Plant Journal 50:80-94

11.    Ongaro V, Bainbridge K, Williamson L, Leyser O (2008) Interactions between axillary branches of Arabidopsis. Molecular Plant 1:388-400

12.    Hayward A, Stirnberg P, Beveridge C, Leyser O (2009) Interactions between auxin and strigolactone in shoot branching control. Plant Physiology 151:400-412

13.    Prusinkiewicz P, Crawford C, Smith R, Ljung K, Bennett T, Ongaro V, Leyser O (2009) Control of bud activation by an auxin transport switch. Proceedings of the National Academy of Science USA 106:17431-17436

14.    Crawford S, Shinohara N, Sieberer T, Williamson L, George G, Hepworth J, Müller D, Domagalska MA, Leyser O (2010) Strigolactones enhance competition between shoot branches by dampening auxin transport. Development 137:2905-2913

15.    Leyser O (2011) Auxin, self-organisation, and the colonial nature of plants. Current Biology 21:R331-R337

16.    Steinacher A, Leyser O, Clayton RH (2012) A computational model of auxin and pH dynamics in a single plant cell. Journal of Theoretical Biology 269:84-94

17.    Stirnberg P, Zhao S, Williamson L, Ward S, Leyser O (2012) FHY3 promotes shoot branching and stress tolerance in Arabidopsis in an AXR1-dependent manner. Plant Journal 71:907-920